In my opinion, the default boxes you get with tcolorbox aren’t that good-looking:

Screenshot of default boxes

So I eventually decided to dive into the extensive documentation and make use of the myriad of config options to find something that looks cleaner. Here’s the result:

Screenshot of adapted boxes

The color on the left can be freely customized, of course. In my (german) Analysis cheatsheets, I like to use the colorful version for important theorems, and have the grey version ready for less vital corollaries.

Screenshot of the Analysis cheatsheet

If you like the look, feel free to steal the code:

\usepackage[most]{tcolorbox}

\tcbset {
  base/.style={
    arc=0mm, 
    bottomtitle=0.5mm,
    boxrule=0mm,
    colbacktitle=black!10!white, 
    coltitle=black, 
    fonttitle=\bfseries, 
    left=2.5mm,
    leftrule=1mm,
    right=3.5mm,
    title={#1},
    toptitle=0.75mm, 
  }
}

\definecolor{brandblue}{rgb}{0.34, 0.7, 1}
\newtcolorbox{mainbox}[1]{
  colframe=brandblue, 
  base={#1}
}

\newtcolorbox{subbox}[1]{
  colframe=black!30!white,
  base={#1}
}

To then utilize the new style, use the following syntax:

% replace mainbox with subbox for the grey version
\begin{mainbox}{A short title} 
    Some exquisite prose you've written...
\end{mainbox}